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NRP507 Advanced Pharmacology

Week 8 Discussion                           

Protein Pump Inhibitors and H2 Blockers

Answer the following questions in a minimum of 175-300 words:

What is the difference in mechanism of action between a PPI and an H2 blocker? Please explain.

Which one offers more blockade of hydrochloric acid?

Why do most of the PPIs need to be prescribed as dose before meals?

What are the implications for long-term use of these medications?

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